PUBLICATION:

GeCell Therapeutics 2023

Accurate Integration of PiggyBac Transposon into Defined Genome Locus by using Engineered PBase fused to Cas9

Xu Naiqing, Hu Xiaohan, Fang Yuan, Liu Jingxian, Sun Kailiang, Xu Tian.

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PUBLICATION:

GeCell Therapeutics 2023

Treatment of Recessive Dystrophic Epidermolysis Bullosa by Transplantation of COL7A1 Transgenic Tissue-engineered Skin Grafts

Xiaogang Deng, Weili Cong, Zhiming Chen, Zheng Zhang, Xian Liu, Wenjing Bai, Yijun Li, Xi Wang, Yingcun Wang, Qianqian Chen, Liwen Zhang, Xihui Gu, Yi Zhang, Kailiang Sun, Xiaoyang Wu, Yong Yang, Tian Xu.

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PUBLICATION:

Nat Commun. 2019

Highly branched poly (β-amino ester)  delivery of minicircle DNA for transfection of neurodegenerative disease related cells

Liu S., Gao Y., Zhou D., Zeng M., Alshehri F., Newland B., et al.

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PUBLICATION:

Nat Biomed Eng. 2019

Genome-edited skin epidermal stem cells protect mice from cocaine-seeking behaviour and cocaine overdose

Li Y., Kong Q., Yue J., Gou X., Xu M., Wu X.

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Proc Natl Acad Sci USA 2017

DNA-PK facilitates PiggyBac transposition by promoting paired-end complex formation

Jin Y., Chen Y., Zhao S., Guan K-L., Zhuang Y., Zhou W., et al.

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PUBLICATION:

Cell Stem Cell 2017

Engineered Epidermal Progenitor Cells Can Correct Diet-Induced Obesity and Diabetes

Yue J., Gou X., Li Y., Wicksteed B., Wu X.

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PUBLICATION:

Biomacromolecules 2016

Highly Branched Poly (β-amino esters) for Non-Viral Gene Delivery: High Transfection Efficiency and Low Toxicity Achieved by Increasing Molecular Weight

Jin Y., Chen Y., Zhao S., Guan K-L., Zhuang Y., Zhou W., et al.

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Sci Adv. 2016

The transition from linear to highly branched poly (β-amino ester)s: Branching matters for gene delivery

Zhou D., Cutlar L., Gao Y., Wang W., O’Keeffe-Ahern J., McMahon S., et al.

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Exp Dermatol. 2016

A non-viral gene therapy for treatment of recessive dystrophic epidermolysis bullosa

Cutlar L., Zhou D., Hu X., Duarte B., Greiser U., Larcher F., et al.

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Chem Commun. 2015

Tailoring highly branched poly (β-amino ester)s: a synthetic platform for epidermal gene therapy

Huang J.-Y., Gao Y., Cutlar L., O’Keeffe-Ahern J., Zhao T., Lin F-H., et al.

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Dis Model Mech 2013

PiggyBac as a high-capacity transgenesis and gene-therapy vector in human cells and mice

Li R., Zhuang Y., Han M., Xu T., Wu X.

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PUBLICATION:

Cell 2005

Efficient transposition of the PiggyBac (PB) transposon in mammalian cells and mice

Ding S., Wu X., Li G., Han M., Zhuang Y.,Xu T.

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